{"id":660,"date":"2025-08-14T10:20:13","date_gmt":"2025-08-14T01:20:13","guid":{"rendered":"https:\/\/fujimakimedical.com\/?p=660"},"modified":"2025-08-14T10:20:13","modified_gmt":"2025-08-14T01:20:13","slug":"%e8%ab%96%e6%96%87%e8%a7%a3%e8%aa%ac%ef%bc%9ause-of-finasteride-in-the-treatment-of-men-with-androgenetic-alopecia%ef%bc%88shapiro-kaufman-2003%ef%bc%89","status":"publish","type":"post","link":"https:\/\/fujimakimedical.com\/?p=660","title":{"rendered":"\u8ad6\u6587\u89e3\u8aac\uff1aUse of Finasteride in the Treatment of Men With Androgenetic Alopecia\uff08Shapiro &#038; Kaufman, 2003\uff09"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u2014 5\u5e74\u9593\u306e\u56fd\u969b\u81e8\u5e8a\u8a66\u9a13\u304c\u793a\u3059\u9577\u671f\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027 \u2014<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">1. \u8ad6\u6587\u6982\u8981<\/h2>\n\n\n\n<p>\u672c\u8ad6\u6587\u306f\u3001<strong>\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c91mg\u306e\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA\uff09\u6cbb\u7642\u306b\u304a\u3051\u308b\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027<\/strong>\u3092\u3001\u521d\u671f\u7528\u91cf\u8a2d\u5b9a\u8a66\u9a13\u304b\u30895\u5e74\u9593\u306e\u5ef6\u9577\u8a66\u9a13\u307e\u3067\u5305\u62ec\u7684\u306b\u30ec\u30d3\u30e5\u30fc\u3057\u305f\u7dcf\u8aac\u3067\u3059\u3002\u7279\u306b\u3001\u9802\u90e8\u304a\u3088\u3073\u524d\u982d\u90e8\u578bAGA\u306b\u304a\u3051\u308b\u9577\u671f\u52b9\u679c\u3068\u3001\u526f\u4f5c\u7528\u767a\u73fe\u7387\u306e\u63a8\u79fb\u304c\u8a73\u7d30\u306b\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3010Shapiro &amp; Kaufman, 2003\u3011\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">2. \u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3068\u4f5c\u7528\u6a5f\u5e8f<\/h2>\n\n\n\n<p>\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306f<strong>\u2161\u578b5\u03b1\u9084\u5143\u9175\u7d20\u963b\u5bb3\u85ac<\/strong>\u3067\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u304b\u3089\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u3078\u306e\u5909\u63db\u3092\u6291\u5236\u3057\u307e\u3059\u3002<br>AGA\u3067\u306fDHT\u304c\u6bdb\u5305\u30df\u30cb\u30c1\u30e5\u30a2\u5316\u3092\u9032\u884c\u3055\u305b\u308b\u305f\u3081\u3001\u305d\u306e\u6291\u5236\u306f\u767a\u6bdb\u4fc3\u9032\u304a\u3088\u3073\u8131\u6bdb\u9032\u884c\u6291\u5236\u306b\u76f4\u7d50\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">3. \u81f3\u9069\u7528\u91cf\u306e\u6c7a\u5b9a<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Drake\u3089\uff081999\uff09\uff1a0.05\u301c5mg\u3067DHT\u6291\u5236\u3092\u6bd4\u8f03\u3057\u3001<strong>0.2mg\u4ee5\u4e0a\u3067\u307b\u307c\u6700\u5927\u6291\u5236<\/strong>\u3002<\/li>\n\n\n\n<li>Roberts\u3089\uff081999\uff09\uff1a\u81e8\u5e8a\u52b9\u679c\u306f<strong>1mg\u30685mg\u3067\u540c\u7b49<\/strong>\u30010.2mg\u4ee5\u4e0b\u3067\u306f\u6709\u52b9\u6027\u4f4e\u4e0b\u3002<\/li>\n\n\n\n<li>\u7d50\u679c\uff1a1mg\u304c<strong>\u56fd\u969b\u6a19\u6e96\u7528\u91cf<\/strong>\u3068\u3057\u3066\u63a1\u7528\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">4. \u7b2cIII\u76f8\u8a66\u9a13\u306e\u7d50\u679c<\/h2>\n\n\n\n<p>\u5bfe\u8c61\u306f18\u301c41\u6b73\u306eAGA\u7537\u6027\uff08\u9802\u90e8\u578b2\u8a66\u9a13n=1,553\u3001\u524d\u982d\u90e8\u578b1\u8a66\u9a13n=326\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u9802\u90e8\u578bAGA\uff0824\u304b\u6708\uff09<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5199\u771f\u8a55\u4fa1\uff1a1\u5e74\u5f8c48%\u30012\u5e74\u5f8c66%\u304c\u6539\u5584\uff08\u30d7\u30e9\u30bb\u30dc\u306f\u5e38\u306b7%\uff09\u3002<\/li>\n\n\n\n<li>\u6bdb\u9aea\u6570\uff1a1\u5e74\u5f8c\uff0b11%\u30012\u5e74\u5f8c\u7dad\u6301\uff08\u30d7\u30e9\u30bb\u30dc\u306f\u6e1b\u5c11\uff09\u3002<\/li>\n\n\n\n<li>\u9032\u884c\u6291\u5236\u7387\uff1a83%\uff08\u30d7\u30e9\u30bb\u30dc28%\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u524d\u982d\u90e8\u578bAGA\uff0812\u304b\u6708\uff09<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5199\u771f\u8a55\u4fa1\uff1a\u6539\u5584\u738737%\uff08\u30d7\u30e9\u30bb\u30dc5%\uff09\u3002<\/li>\n\n\n\n<li>\u9032\u884c\u6291\u5236\u7387\uff1a70%\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u5b89\u5168\u6027<\/strong><br>\u6027\u6a5f\u80fd\u95a2\u9023\u526f\u4f5c\u7528\u306f1\u301c2%\u53f0\uff08\u30ea\u30d3\u30c9\u30fc\u4f4e\u4e0b1.8%\u3001ED 1.3%\u3001\u5c04\u7cbe\u969c\u5bb31.2%\uff09\u3001\u5927\u534a\u306f\u53ef\u9006\u7684\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">5. 5\u5e74\u9593\u306e\u5ef6\u9577\u8a66\u9a13<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6bdb\u9aea\u6570\u306f<strong>5\u5e74\u9593\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3088\u308a\u7dad\u6301\u307e\u305f\u306f\u5897\u52a0<\/strong>\u3002<\/li>\n\n\n\n<li>5\u5e74\u5f8c\u306e\u5199\u771f\u8a55\u4fa1\uff1a<strong>90%\u304c\u7dad\u6301\u307e\u305f\u306f\u6539\u5584<\/strong>\uff08\u30d7\u30e9\u30bb\u30dc\u306f75%\u304c\u60aa\u5316\uff09\u3002<\/li>\n\n\n\n<li>\u6bdb\u9aea\u6570\u5dee\uff1a+277\u672c\/\u30bf\u30fc\u30b2\u30c3\u30c8\u9818\u57df\uff08\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9vs\u30d7\u30e9\u30bb\u30dc\uff09\u3002<\/li>\n\n\n\n<li>\u65b0\u305f\u306a\u526f\u4f5c\u7528\u306f\u5831\u544a\u3055\u308c\u305a\u3001\u526f\u4f5c\u7528\u767a\u73fe\u7387\u306f\u521d\u5e74\u5ea6\u3088\u308a\u4f4e\u4e0b\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">6. \u4f5c\u7528\u6a5f\u5e8f\u306b\u95a2\u3059\u308b\u88dc\u8db3\u7814\u7a76<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Whiting\u3089\uff081999\uff09\uff1a\u751f\u691c\u3067<strong>\u7d42\u6bdb\u5897\u52a0\u30fb\u30df\u30cb\u30c1\u30e5\u30a2\u6bdb\u6e1b\u5c11\u50be\u5411<\/strong>\u3092\u78ba\u8a8d\u3002<\/li>\n\n\n\n<li>Van Neste\u3089\uff082000\uff09\uff1a\u5199\u771f\u6bdb\u9aea\u8a08\u3067**\u6210\u9577\u671f\u6bdb\u6bd4\u7387\uff0b47%**\u3092\u8a3c\u660e\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">7. \u5973\u6027\u3067\u306e\u52b9\u679c<\/h2>\n\n\n\n<p>\u9589\u7d4c\u5f8c\u5973\u6027\uff08Price\u3089 2000\uff09\u3067\u306f\u3001<strong>1mg\u3067\u6709\u52b9\u6027\u306a\u3057<\/strong>\u3002\u6bdb\u9aea\u6570\u30fb\u5199\u771f\u8a55\u4fa1\u30fb\u751f\u691c\u3059\u3079\u3066\u3067\u30d7\u30e9\u30bb\u30dc\u3068\u306e\u5dee\u306a\u3057\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">8. \u81e8\u5e8a\u7684\u307e\u3068\u3081<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>1mg\u306f\u7537\u6027AGA\u306e\u9577\u671f\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u304c\u78ba\u7acb<\/strong>\u3002<\/li>\n\n\n\n<li>\u9802\u90e8\u30fb\u524d\u982d\u90e8\u306e\u4e21\u65b9\u3067\u52b9\u679c\u3042\u308a\u3001\u6301\u7d9a\u6295\u4e0e\u304c\u5fc5\u8981\u3002<\/li>\n\n\n\n<li>\u4f4e\u7528\u91cf\u306e\u9577\u671f\u6709\u52b9\u6027\u306f\u30a8\u30d3\u30c7\u30f3\u30b9\u4e0d\u8db3\u3002<\/li>\n\n\n\n<li>\u5973\u6027\uff08\u7279\u306b\u9589\u7d4c\u5f8c\uff09\u3078\u306e\u52b9\u679c\u306f\u78ba\u8a8d\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Shapiro J, Kaufman KD. Use of finasteride in the treatment of men with androgenetic alopecia (male pattern hair loss). <em>J Investig Dermatol Symp Proc<\/em>. 2003;8(1):20-23.<\/li>\n\n\n\n<li>Drake L, Hordinsky M, Fiedler V, et al. The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia. <em>J Am Acad Dermatol<\/em>. 1999;41(4):550-554.<\/li>\n\n\n\n<li>Roberts JL, Fiedler V, Imperato-McGinley J, et al. Clinical dose ranging studies with finasteride, a type 2 5\u03b1-reductase inhibitor, in men with male pattern hair loss. <em>J Am Acad Dermatol<\/em>. 1999;41(4):555-563.<\/li>\n\n\n\n<li>Finasteride Male Pattern Hair Loss Study Group. Long-term (5-year) multinational experience with finasteride 1 mg in the treatment of men with androgenetic alopecia. <em>Eur J Dermatol<\/em>. 2002;12(1):38-49.<\/li>\n\n\n\n<li>Price VH, Roberts JL, Hordinsky M, et al. Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia. <em>J Am Acad Dermatol<\/em>. 2000;43(5 Pt 1):768-776.<\/li>\n\n\n\n<li>Van Neste D, Fuh V, Sanchez-Pedreno P, et al. Finasteride increases anagen hair in men with androgenetic alopecia. <em>Br J Dermatol<\/em>. 2000;143(4):804-810.<\/li>\n\n\n\n<li>Whiting DA, Waldstreicher J, Sanchez M, Kaufman KD. Measuring reversal of hair miniaturization in androgenetic alopecia by follicular counts in horizontal sections of serial scalp biopsies. <em>J Investig Dermatol Symp Proc<\/em>. 1999;4(3):282-284.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>\u2014 5\u5e74\u9593\u306e\u56fd\u969b\u81e8\u5e8a\u8a66\u9a13\u304c\u793a\u3059\u9577\u671f\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027 \u2014 1. \u8ad6\u6587\u6982\u8981 \u672c\u8ad6\u6587\u306f\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c91mg\u306e\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA\uff09\u6cbb\u7642\u306b\u304a\u3051\u308b\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u3092\u3001\u521d\u671f\u7528\u91cf\u8a2d\u5b9a\u8a66\u9a13\u304b\u30895\u5e74\u9593\u306e\u5ef6\u9577\u8a66\u9a13\u307e\u3067\u5305\u62ec\u7684\u306b\u30ec\u30d3\u30e5\u30fc\u3057\u305f\u7dcf\u8aac\u3067&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[5],"tags":[],"class_list":["post-660","post","type-post","status-publish","format-standard","hentry","category-5"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=\/wp\/v2\/posts\/660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=660"}],"version-history":[{"count":1,"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=\/wp\/v2\/posts\/660\/revisions"}],"predecessor-version":[{"id":661,"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=\/wp\/v2\/posts\/660\/revisions\/661"}],"wp:attachment":[{"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=660"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fujimakimedical.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}